Based on the nomenclature for other purinergic receptor families p1 for adenosine and p2 for nucleotide receptors adenine receptors were designated p0 receptors 64 g protein coupled p0 re . Among these receptors p2x 5 and p2x 6 and p2x 2 and p2x 5 have been found to be expressed in chick and rat skeletal muscle development respectively 5 11 on the contrary the expression and function of p2y nucleotide receptors in developing skeletal muscle cells has rarely been studied. Zyxwvuts z zyxwvutsrqpo zyxw zyxwvuts 02003 oxford university press nucleic acids research supplement no 3 3 4 zyxwv molecular recognition in p2 nucleotide receptors kenneth a jacobson molecular recognition section laboratory of bioorganic chemistry niddk national institutes of health dept of health and human services bethesda md 20892 usa in nearly all organ systems extracellular . Cyclopiazonic acid cpa 5 um an inhibitor of the ca 2 atpase of the sarco endoplasmic reticulum was added to the bathing solution 5 min before and during the application of the two p2 nucleotide receptor agonists fig 4
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