T cell and cytokine regulation of mucosal antibody responses with emphasis on intraepithelial lymphocytes helper functions jerry r mcghee and others origin and development of gut intraepithelial lymphocytes delphine guy grand benedita rocha pierre vassalli phenotypic and cytotoxic characteristics of intraepithelial lymphocytes . Intraepithelial lymphocytes exploring the third way in immunology j moseley r in mucosal immunology intraepithelial lymphocytes advances in host defense mechanisms eds kiyono . O t cells are situated between enterocytes immediately below the mucosal surface where they are known as intraepithelial lymphocytes iels playing an early critical role in the defense of the mucosa iels regulate host microbial interactions at the intestinal mucosa surface and are critical components in preventing invasion by the . Hilde cheroutre leo lefrancois in mucosal immunology fourth edition 2015 abstract intraepithelial lymphocytes or iel consist exclusively of t lymphocytes that reside interspersed between epithelial cells in the epithelium of the small and large intestine the biliary tract the oral cavity the lung the upper respiratory tract and the reproductive tract as well as in the skin
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