Drug interactions the following antiepileptic drug drug interactions are of clinical significance with topiramate co medication in co medication phenytoin plasma levels may increase by 25 and topiramate decrease by 48 carbamazepine may decrease topiramate plasma by nearly half. According to pharmacopoeia of prophylactic antiepileptic drugs this drug can treat focal generalized idiopathic or symptomatic epilepsy in people of all ages this drug may also cause fewer . Antiepileptic drugs pharmacopoeia provides a concise guide to the properties and clinical applications of all antiepileptic drugs aed currently used in the prophylactic treatment of epileptic seizures the presentation of each aed follows a clinically orientated template. This pharmacopoeia includes the majority of common antiepileptic drugs used worldwide because this volume is intended for an international audience some drugs may not be fda or emea european medicines agency approved
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